EFFICACY OF METHOTREXATE ALONE OR WITH LOW-DOSE PREDNISONE IN ALOPECIA AREATA TOTALIS

This study aimed to evaluate the efficacy of methotrexate alone or in combination with low-dose prednisone treating alopecia areata totalis. A randomized controlled trial was conducted among 100 patients diagnosed Participants were randomly assigned two treatment groups: Group received alone, and B prednisone. The primary outcome measure proportion achieving hair regrowth at end period. Secondary outcomes included time regrowth, duration response, adverse events. Of patients, 50 B. findings revealed that both regimens, prednisone, showed promoting In A, 30 (60%) achieved while B, 40 (80%) regrowth. therapy group demonstrated a higher than methotrexate-alone group. for also shorter compared Adverse events minimal comparable between groups. results this suggest are effective options superior reducing alone. support use as potential approach However, further research larger sample size is warranted validate these establish optimal dosing long-term safety patient population.